Lehigh Valley Hospital: When It Matters Most
lvh.org home page Careers at LVH Education @ LVH For Professionals working with LVH
Conditions We Treat

Beat MS Fatigue

Ways to stay active and alert

Fatigue

Fatigue is an extremely common symptom of Multiple Sclerosis occurring in up to 95% of patients, according to one survey. There are a variety of causes of fatigue and trying to understand the cause may be helpful. In addition there are a number of ways that fatigue may be managed in patients with Multiple Sclerosis.

Fatigue may be caused by a number of problems related to MS:

1. Poor SleepPatients occasionally will have spasticity at night, nighttime urination or other problems that break up their sleep at night. This would then lead to daytime sleepiness. If this is the problem, then treatment of the underlying nighttime disturbance may be helpful in the controlling the daytime fatigue.

2. DepressionDepression is a common manifestation of MS and one of the symptoms of depression is fatigue and daytime sleepiness. If you have beginning symptoms of depression such as sad mood, inability to enjoy usual activities, a weight gain or loss, a sense of despair, or suicidal thoughts, discuss these with your physician and consider treatment.

3. Over-exhaustionOften patients with MS will have muscle fatigue, particularly if they work long hours or over exhaust themselves. By carefully timing their activities, doing most of the activities in the morning when fatigue is less and taking regular naps, these symptoms may be improved.

4. MS itselfThe most significant cause of fatigue in multiple sclerosis is related to the disease itself. There appears to be a direct immunological reason for the fatigue, which may relate to some of the chemicals released into the brain by the T-cells. Theses chemicals, called cytokines, are the same chemicals released in viral infections and may cause the fatigue related to such viruses. This is thus a major symptom of the disease unrelated to depression, poor sleep habits, or overwork.

Treatment of fatigue in MS

1. ExerciseA regular exercise program has been shown to improve fatigue symptoms. It will take time to develop the training effect but exercising 3 times per week for about 45 minutes has been shown to have a beneficial effect.

2. Energy conservationIt is important to parcel out efforts so that the energy is there when needed. Often people do what they need to do most in the morning when their energy level is highest. They may try to take breaks or short naps to reenergize themselves. Doing fewer optional things ina day may also help. By paying attention to energy requirements of different activities, the most necessary things can be done first.

3. Medications:

  • Amantandine (Symmetrel)—Amantidine is a medication that has been shown in well controlled studies to improve fatigue symptoms in patients with MS. The usual dose is 100 mg, 2–3 time per day. Side effects are relatively minor and include a bluish discoloration in the legs, which is not dangerous (Livido Reticularis). Occasionally the patient will have nausea or excessive dreaming on this medication.

  • Pemoline (Cylert)—In controlled trials, Pemoline has not been shown to be effective in MS, but in individual patients, it may be useful in decreasing fatigue symptoms. It should be used with the guidance of a physician experienced in its side effect profile. Since it ia a stimulant medication, it may cause side effects of insomnia and rapid heart beat.

  • This page last updated 3/31/08 02:35 PM
    ARTICLE TOOLS:

    email this article to a friend print this article    Del.icio.us   Stumble It!






    hon cod ©2008 Lehigh Valley Hospital and Health Network
    LVH Info Line: 610-402-CARE
    Cedar Crest & I-78, P.O. Box 689, Allentown, PA 18105-1556

    Lehigh Valley Hospital has campuses in Allentown and Bethlehem, Pa. and serves the Pennsylvania communities of Easton, Doylestown, Quakertown, Hazelton, Lehighton, Perkasie, Pottstown, Pottsville, Reading, Scranton, Wilkes Barre, Stroudsburg, and the Poconos and also Phillipsburg and Flemington, N.J., and western New Jersey. You don't have to travel to Philadelphia or New York for quality health care.

     
    Increase the Size of Text by clicking here. Descrease the Size of Text by clicking here Email this story to family and friends. Print this story formatted for your printer.